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Article

Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines

25 Nov 2003

Abstract excerpt

Effects of ionising radiation on extracellular matrix (ECM)-modulated cell survival and on adhesion and invasion are not well understood. In particular, the aggressiveness of glioblastoma multiforme has been associated with tumour cell invasion into adjacent normal brain tissue. To examine these effects in more depth, four human glioblastoma cell lines (A-172, U-138, LN-229 and LN-18) were irradiated on...

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PMID: 14647148
DOI: 10.1038/sj.bjc.6601429

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