Article
Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.
Journal of molecular biology - 12 Dec 2003
Ribard Carin, Rochet Michel, Labedan Bernard, Daignan-Fornier Bertrand, Alzari Pedro, Scazzocchio Claudio, Oestreicher Nathalie
Abstract excerpt
No gene coding for an adenine deaminase has been described in eukaryotes. However, physiological and genetical evidence indicates that adenine deaminases are present in the ascomycetes. We have cloned and characterised the genes coding for the adenine deaminases of Aspergillus nidulans, Saccharomyces cerevisiae and Schizosaccharomyces pombe. The A.nidulans gene was expressed in Escherichia coli and the purified...
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