Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.

doi:10.1016/j.jmb.2003.10.005

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Article

Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family.

Journal of molecular biology - 12 Dec 2003

Ribard Carin, Rochet Michel, Labedan Bernard, Daignan-Fornier Bertrand, Alzari Pedro, Scazzocchio Claudio, Oestreicher Nathalie

Abstract excerpt

No gene coding for an adenine deaminase has been described in eukaryotes. However, physiological and genetical evidence indicates that adenine deaminases are present in the ascomycetes. We have cloned and characterised the genes coding for the adenine deaminases of Aspergillus nidulans, Saccharomyces cerevisiae and Schizosaccharomyces pombe. The A.nidulans gene was expressed in Escherichia coli and the purified...

Topics

Amino Acid Sequence
Aminohydrolases
Base Sequence
Cloning, Molecular
DNA Primers
DNA, Complementary
Fungi
Molecular Sequence Data
Mutation
Sequence Homology, Amino Acid
Species Specificity

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Identifiers

PMID: 14643670
DOI: 10.1016/j.jmb.2003.10.005

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