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Article

No evidence for a seriously increased malignancy risk in LGI1-caused epilepsy.

Epilepsy research - 1 Oct 2003

Brodtkorb Eylert, Nakken Karl O, Steinlein Ortrud K

Abstract excerpt

The Leucine-rich Glioma Inactivated-1 (LGI1) gene is supposed to be a tumor suppressor gene involved in glial tumors. Mutations in this gene were recently found to cause autosomal dominant lateral temporal lobe epilepsy (ADLTE). We have now analysed the comorbidity in a large Norwegian ADLTE family. No evidence was found that LGI1 is a high-penetrance tumor suppressor gene associated with a serious risk for...

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Source

Identifiers

PMID: 14643004
DOI: 10.1016/j.eplepsyres.2003.09.006

Genes

LGI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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