Article
Incorporation of gene-specific variability improves expression analysis using high-density DNA microarrays.
BMC biology - 28 Nov 2003
Budhraja Vikram, Spitznagel Edward, Schaiff W Timothy, Sadovsky Yoel
Abstract excerpt
BACKGROUND: The assessment of data reproducibility is essential for application of microarray technology to exploration of biological pathways and disease states. Technical variability in data analysis largely depends on signal intensity. Within that context, the reproducibility of individual probe sets has not been hitherto addressed. RESULTS: We used an extraordinarily large replicate data set derived from...
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