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Article

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.

Cancer research - 15 Nov 2003

Lipton Lara, Halford Sarah E, Johnson Victoria, Novelli Marco R, Jones Angela, Cummings Carole, Barclay Ella, Sieber Oliver, Sadat Amir, Bisgaard Marie-Luise, Hodgson Shirley V, Aaltonen Lauri A, Thomas Huw J W, Tomlinson Ian P M

Abstract excerpt

Colorectal carcinomas develop according to particular genetic pathways, including the chromosomal instability (CIN+), microsatellite instability (MSI+) and MSI- CIN- routes. We have determined the genetic pathway in patients with MYH-associated polyposis (MAP), a syndrome of colorectal adenomas a...

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Source

Identifiers

PMID: 14633673

Genes

APC
BRAF
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14633673-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.PMID 14633673Read ↗

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