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dl-VSVG-LacZ, a vesicular stomatitis virus glycoprotein epitope-incorporated adenovirus, exhibits marked enhancement in gene transduction efficiency.

Human gene therapy - 20 Nov 2003

Yun Chae-Ok, Cho Eun-A, Song Jae-Jin, Kang Dae-Bong, Kim Eunhee, Sohn Joo-Hyuk, Kim Joo-Hang

Abstract excerpt

Recombinant adenovirus (Ad) has emerged as the vector system of choice in cancer gene therapy. Its full utility, however, has been limited because of the low efficiency of adenovirus-mediated gene transfer to cancer cells - the main reason being that cancer cells in general express inherently low levels of the coxsackie and adenovirus receptor (CAR) on their surface. Development of novel strategies to achieve...

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PMID: 14633406
DOI: 10.1089/104303403322542284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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