Article
Prospects for whole genome linkage disequilibrium mapping in domestic dog breeds.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2003
Hyun Changbaig, Filippich Lucio J, Lea Rod A, Shepherd Graeme, Hughes Ian P, Griffiths Lyn R
Abstract excerpt
Linkage disequilibrium (LD) mapping is commonly used as a fine mapping tool in human genome mapping and has been used with some success for initial disease gene isolation in certain isolated in-bred human populations. An understanding of the population history of domestic dog breeds suggests that LD mapping could be routinely utilized in this species for initial genome-wide scans. Such an approach offers...
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