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Article

Placental Trophoblast from Successful Human Pregnancies Expresses the Tolerance Signaling Molecule, CD200 (OX‐2)*

11 Aug 2003

Abstract excerpt

PROBLEM: Th1 cytokine-dependent abortions in the CBA x DBA/2 mouse model have been linked to down-regulation of expression of the CD200 (OX-2) 'tolerance' signal on trophoblast and in decidua prior to onset of the abortion process. Abortions could be prevented by administration of a soluble CD200. Is CD200 expressed on trophoblast in successful human pregnancy? METHOD OF STUDY: As one cannot easily obtain...

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Identifiers

PMID: 14629022
DOI: 10.1034/j.1600-0897.2003.00086.x

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