Article
Cancer and epigenesis: a developmental perspective.
Advances in pediatrics - 1 Jan 2003
Oligny Luc Laurier
Abstract excerpt
Traditionally, molecular geneticists have studied the genome, that is, DNA. This has included its sequencing, with identification of promoters, enhancers, introns, exons, and mutations. During the last 10 to 15 years, it has become clear that this study of "naked" DNA imposed major limitations on our understanding of gene regulation, and that DNA must be studied in conjunction with its protein backbone...
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