Article
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli.
Molecular microbiology - 1 Oct 2003
Layton Jill C, Foster Patricia L
Abstract excerpt
An insertion in rpoS, which encodes the general stress response sigma factor sigma 38, was isolated as an antimutator for 'stationary-phase' or 'adaptive' mutation. In the rpoS mutant strain the levels of error-prone DNA polymerase Pol IV were reduced. Pol IV is encoded by the dinB gene, and the amount of its transcript was also reduced in rpoS mutant cells. In wild-type cells, the levels of Pol IV increased in...
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