Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics.

Journal of cell science - 1 Dec 2003

Emery Gregory, Parton Robert G, Rojo Manuel, Gruenberg Jean

Abstract excerpt

Trans-membrane proteins of the p24 family are abundant, oligomeric proteins predominantly found in cis-Golgi membranes. They are not easily studied in vivo and their functions are controversial. We found that p25 can be targeted to the plasma membrane after inactivation of its canonical KKXX motif (KK to SS, p25SS), and that p25SS causes the co-transport of other p24 proteins beyond the Golgi complex, indicating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Cholesterol
Share to Golgi Apparatus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Membrane Microdomains

Share to Microscopy, Fluorescence

Share to Microscopy, Immunoelectron

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 14600267
DOI: 10.1242/jcs.00802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics.PMID 14600267Read ↗

Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22.Semantic proximity Read ↗

The role of the Golgi apparatus in disease (Review).Semantic proximity Read ↗

The Golgi Apparatus: A Voyage through Time, Structure, Function and Implication in Neurodegenerative DisordersSemantic proximity Read ↗

Thinking about p24 proteins and how transport vesicles select their cargo.Semantic proximity Read ↗

Mechanisms of multipass membrane protein biogenesisSemantic proximity Read ↗

Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport.Semantic proximity Read ↗

At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosisSemantic proximity Read ↗

The hydrophobic cysteine-rich domain of SNAP25 couples with downstream residues to mediate membrane interactions and recognition by DHHC palmitoyl transferases.Semantic proximity Read ↗

MicroProteins: Expanding functions and novel modes of regulation.Semantic proximity Read ↗

p24 proteins, intracellular trafficking, and behavior: Drosophila melanogaster provides insights and opportunities.Semantic proximity Read ↗

TCF25 emerges as a cytoplasmic regulator of GPRASP2 stabilitySemantic proximity Read ↗

An intramembrane chaperone complex facilitates membrane protein biogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.