Article
Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2003
Veikkola Tanja, Lohela Marja, Ikenberg Kristian, Mäkinen Taija, Korff Thomas, Saaristo Anne, Petrova Tatania, Jeltsch Michael, Augustin Hellmut G, Alitalo Kari
Abstract excerpt
Vascular endothelial cells are characterized by a high degree of functional and phenotypic plasticity, which is controlled both by their pericellular microenvironment and their intracellular gene expression programs. To gain further insight into the mechanisms regulating the endothelial cell phenotype, we have compared the responses of lymphatic endothelial cells (LECs) and blood vascular endothelial cells (BECs)...
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