Article
Induction of neuron-specific enolase promoter and neuronal markers in differentiated mouse bone marrow stromal cells.
Journal of molecular neuroscience : MN - 1 Jan 2003
Levy Yossef S, Merims Doron, Panet Hanna, Barhum Yael, Melamed Eldad, Offen Daniel
Abstract excerpt
Mesenchymal stem cells in the adult bone marrow are differentiated to connective tissue, muscle, bone, cartilage, and fat cells. Recent studies in cultures, animal models, and humans demonstrated the plasticity of these cells and their capacity to express neuronal markers. However, questions were raised as to whether the neuronal phenotypes reflect transient changes or even fusion with neurons. In this study, we...
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