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Article

An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control.

The EMBO journal - 3 Nov 2003

Staeva-Vieira Eric, Yoo Siuk, Lehmann Ruth

Abstract excerpt

Rad51 is a conserved protein essential for recombinational repair of double-stranded DNA breaks (DSBs) in somatic cells and during meiosis in germ cells. Yeast Rad51 mutants are viable but show meiosis defects. In the mouse, RAD51 deletions cause early embryonic death, suggesting that in higher eukaryotes Rad51 is required for viability. Here we report the identification of SpnA as the Drosophila Rad51 gene,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14592983
DOI: 10.1093/emboj/cdg564
PMCID: PMC275421

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control.PMID 14592983Read ↗

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Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.Semantic proximity Read ↗

Novel insights into RAD51 activity and regulation during homologous recombination and DNA replicationSemantic proximity Read ↗

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