Article
NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy.
Neuroscience letters - 13 Nov 2003
Spadafora P, Annesi G, Pasqua A A, Serra P, Cirò Candiano I C, Carrideo S, Tarantino P, Civitelli D, De Marco E V, Nicoletti G, Annesi F, Quattrone A
Abstract excerpt
Contradictory evidence has been reported on the role of the polymorphic mixed dinucleotide repeat (NACP-REP1) of the alpha-synuclein gene as a risk factor for sporadic Parkinson's disease (PD). In the present study we genotyped the NACP-REP1 polymorphism in 189 PD patients from southern Italy and 182 healthy control subjects. We failed to demonstrate an association of any NACP-REP1 allele with PD.
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