Article
A whole genome association study in multiple sclerosis patients from north Portugal.
Journal of neuroimmunology - 1 Oct 2003
Martins Silva Berta, Thorlacius Theodora, Benediktsson Kjartan, Pereira Clara, Fossdal Ragnheidur, Jonsson Hjortur H, Silva Ana, Leite Isabel, Cerqueira J, Costa Paulo P, Marta Monica, Foltynie Thomas, Sawcer Stephen, Compston Alastair, Jonasdottir Aslaug
Abstract excerpt
Genetic factors are known to influence susceptibility to multiple sclerosis (MS) but the genes involved are largely undefined. Here, we report an association study based on 200 patients and 200 controls from the Porto region in Portugal. A total of 3974 markers were successfully typed from which we have identified 46 markers showing evidence of association. When compared to a physical map three regions were found...
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