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Article

[Exploration of methodology for assay of single nucleotide polymorphism in thiopurine methyltransferase gene].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2003

Ma Xiao-Li, Zu Ping, Hu Ya-Mei, Wu Min-Yuan, Li Zhi-Gang, Bu Ding-Fang

Abstract excerpt

The aim of the present study was to gain an insight into the thiopurine methytransferase (TPMT) genotyping assay, which was based on polymerase chain reaction (PCR), allele-specific PCR, restriction digestion of PCR products, denaturing high-performance liquid chromatography (DHPLC) and SNaPshot sequencing and in combination with direct DNA sequencing. Among the f our methods to test TPMT genetic SNPs based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14575536

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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