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Article

Sustained expansion and transgene expression of coagulation factor VIII-transduced cord blood-derived endothelial progenitor cells.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2003

Herder Christian, Tonn Torsten, Oostendorp Robert, Becker Sven, Keller Ulrich, Peschel Christian, Grez Manuel, Seifried Erhard

Abstract excerpt

OBJECTIVE: Although hemophilia A seems particularly suitable for gene therapy because even low amounts of plasma coagulation factor VIII (FVIII) provide a significant clinical benefit to the patients, the ideal target cell for recombinant FVIII expression and gene therapy approaches remains to be identified. In this study, we tested the capacity of cord blood-derived endothelial progenitor cells (CBECs) for FVIII...

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Share to Antigens, CD34
Share to Blood Coagulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14551158
DOI: 10.1161/01.ATV.0000100403.78731.9F

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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