Article
[Effect of the Tabby mutation on the dentition of mice].
Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie - 1 Jan 2000
Lesot H, Peterková R, Kristenová P, Lisi S, Peterka M
Abstract excerpt
The X-linked hypohidrotic ectodermal dysplasia in man leads to dental defects and is homologous to the Tabby (Ta) mutation in mouse. We currently investigate the effects of the Ta mutation on odontogenesis. The incisor germ of Ta showed an abnormal size and shape, a change in the balance between prospective crown- and root-analogue tissues and retarded cytodifferentiation. Although the enamel organ in Ta incisors...
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