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Article

Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF.

Developmental biology - 15 Dec 1999

Pispa J, Jung H S, Jernvall J, Kettunen P, Mustonen T, Tabata M J, Kere J, Thesleff I

Abstract excerpt

Tabby is a mouse mutant characterized by deficient development of the ectodermal organs: teeth, hair, and a subset of glands. Ectodysplasin, the protein encoded by the Tabby gene, was recently identified as a novel TNF-like transmembrane protein but little is known about its function. We have examined the Tabby tooth phenotype in detail by analysis of the adult and embryonic teeth. Tabby first molars had an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10642790
DOI: 10.1006/dbio.1999.9514

Genes

EGF
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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