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Article

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.

Brain : a journal of neurology - 1 Jan 2004

Jonsson P Andreas, Ernhill Karin, Andersen Peter M, Bergemalm Daniel, Brännström Thomas, Gredal Ole, Nilsson Peter, Marklund Stefan L

Abstract excerpt

Mutant forms of superoxide dismutase-1 (SOD1) cause amyotrophic lateral sclerosis (ALS) by an unknown noxious mechanism. Using an antibody against a novel epitope in the G127insTGGG mutation, mutant SOD1 was studied for the first time in spinal cord and brain of an ALS patient. The level was belo...

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Source

Identifiers

PMID: 14534160
DOI: 10.1093/brain/awh005

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14534160-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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