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Article

Association between apolipoprotein E alleles and calcific valvular heart disease.

Circulation - 14 Oct 2003

Novaro Gian M, Sachar Ravish, Pearce Gregory L, Sprecher Dennis L, Griffin Brian P

Abstract excerpt

BACKGROUND: Studies on apolipoprotein E (apoE) alleles have reported an increased risk of coronary heart disease in patients with the apoE4 allele. Given the risk factor and histological similarities between coronary and calcific valvular heart disease (aortic stenosis [AS] and mitral annular calcification [MAC]), we postulated that apoE alleles might be associated with the development of these valvular lesions....

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Source

Identifiers

PMID: 14530190
DOI: 10.1161/01.CIR.0000097560.96431.3E

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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