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Article

DNA probe for strain typing of Cryptococcus neoformans

1 Nov 1992

Abstract excerpt

A 7-kb linear plasmid, harbored by a URA5 transformant, hybridized to all the chromosomes of Cryptococcus neoformans separated by contour-clamped homogeneous electric field electrophoresis. Its linear maintenance was determined to have been facilitated by the presence of telomere-like sequences at its free ends. Hybridization of this plasmid to AccI-digested genomic DNAs of 26 C. neoformans strains generated 21...

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Identifiers

PMID: 1452666
DOI: 10.1128/jcm.30.11.2960-2967.1992

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