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Article

Comparative hybridization reveals extensive genome variation in the AIDS-associated pathogen Cryptococcus neoformans.

Genome biology - 1 Jan 2008

Hu Guanggan, Liu Iris, Sham Anita, Stajich Jason E, Dietrich Fred S, Kronstad James W

Abstract excerpt

BACKGROUND: Genome variability can have a profound influence on the virulence of pathogenic microbes. The availability of genome sequences for two strains of the AIDS-associated fungal pathogen Cryptococcus neoformans presented an opportunity to use comparative genome hybridization (CGH) to examine genome variability between strains of different mating type, molecular subtype, and ploidy. RESULTS: Initially, CGH...

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Identifiers

PMID: 18294377
DOI: 10.1186/gb-2008-9-2-r41
PMCID: PMC2374700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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