Article
Serosubtypes and PorA types of Neisseria meningitidis serogroup B isolated in Brazil during 1997--1998: overview and implications for vaccine development.
Journal of clinical microbiology - 1 Aug 2001
Sacchi C T, Lemos A P, Popovic T, De Morais J C, Whitney A M, Melles C E, Brondi L M, Monteiro L M, Paiva M V, Solari C A, Mayer L W
Abstract excerpt
Meningococcal disease caused by N. meningitidis serogroup B (MenB) has been endemic in Brazil since 1997. In this study, we determined the prevalence of serosubtypes of MenB isolated in 10 Brazilian states and the Federal District during 1997 and 1998 and investigated the extent of PorA VR sequence variation among the most prevalent serosubtypes to evaluate the possible use of an outer membrane vesicle (OMV)-,...
Topics
- Brazil
- Genetic Variation
- Humans
- Meningococcal Infections
- Meningococcal Vaccines
- Molecular Sequence Data
- Neisseria meningitidis
- Porins
- Prevalence
- Serotyping