Article
Taking simvastatin in the morning compared with in the evening: randomised controlled trial
2 Oct 2003
Abstract excerpt
Statins are widely prescribed for the primary and secondary prevention of coronary artery disease. They act by inhibiting the enzyme HMG CoA reductase, which controls synthesis of cholesterol in the liver. Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesised when dietary intake is at its lowest. 1 One small...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.