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Article

Gammadelta T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-alpha and IFN-gamma-producers in response to Pseudomonas aeruginosa.

Respiratory research - 1 Jan 2003

Raga Salvador, Julià M Rosa, Crespí Catalina, Figuerola Joan, Martínez Natalia, Milà Joan, Matamoros Núria

Abstract excerpt

BACKGROUND: Gammadelta T cells have an important immunoregulatory and effector function through cytokine release. They are involved in the responses to Gram-negative bacterium and in protection of lung epithelium integrity. On the other hand, they have been implicated in airway inflammation. METHODS: The aim of the present work was to study intracytoplasmic IL-2, IL-4, IFN-gamma and TNF-alpha production by...

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Identifiers

PMID: 14525626
DOI: 10.1186/1465-9921-4-9
PMCID: PMC203157

Genes

TNF

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