Article
Increase in error threshold for quasispecies by heterogeneous replication accuracy.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Sept 2003
Aoki Kazuhiro, Furusawa Mitsuru
Abstract excerpt
In this paper we investigate the error threshold for quasispecies with heterogeneous replication accuracy. We show that the coexistence of error-free and error-prone polymerases can greatly increase the error threshold without a catastrophic loss of genetic information. We also show that the error threshold is influenced by the number of replicores. Our research suggests that quasispecies with heterogeneous...
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