Article
Unique conformation of cancer autoantigen B23 in hepatoma: A mechanism for specificity in the autoimmune response
30 Sept 2003
Abstract excerpt
The association of a specific autoantibody response with distinct disease phenotypes is observed in both autoimmune diseases and cancer. Although the underlying mechanisms remain unclear, it is likely that unique properties of disease-specific autoantigens expressed in the relevant target cells play a role. It has recently been observed that the majority of autoantigens targeted across the spectrum of systemic...
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