Article
Hemoglobin variant HbG-coushatta (beta-22 Glu --> Ala) found by dissociation of blood glucose from values of HbA1C measured by HPLC.
Internal medicine (Tokyo, Japan) - 1 Sept 2003
Ogawa Koichi, Bando Tomoko, Ogawa Maki, Miyazaki Ayako, Nakanishi Toyohumi, Shimizu Akira
Abstract excerpt
OBJECTIVE: Unexpectedly low values of HbA1C, measured by HPLC compared with their blood glucose levels were found in three related persons. We investigated whether this discrepancy was due to abnormal hemoglobin. PATIENTS AND METHODS: HbA1C was measured by latex agglutination and ordinary HPLC. For further examination, a hemoglobin specimen from the 82-year-old female case was prepared and analyzed by PolyCAT A...
Topics
- Aged
- Aged, 80 and over
- Blood Glucose
- Chromatography, High Pressure Liquid
- Female
- Genetic Predisposition to Disease
- Glycated Hemoglobin
- Hemoglobins, Abnormal
- Humans
- Latex Fixation Tests
