Article
A polymorphism in the promoter of the CD14 gene (CD14/-159) is associated with the development of coronary artery lesions in patients with Kawasaki disease.
The Journal of pediatrics - 1 Sept 2003
Nishimura Shinji, Zaitsu Masafumi, Hara Megumi, Yokota Goro, Watanabe Mamie, Ueda Yoshiaki, Imayoshi Miyoko, Ishii Eiichi, Tasaki Hakaru, Hamasaki Yuhei
Abstract excerpt
OBJECTIVE: To investigate whether a polymorphism in the CD14 gene is associated with Kawasaki disease (KD). STUDY DESIGN: We extracted DNA from the whole blood of 69 control children and 67 patients with KD. We determined a polymorphism in the CD14 gene at position -159 upstream from the major tr...
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