Article
Genetic analysis of MMP gene polymorphisms in patients with Kawasaki disease.
Pediatric research - 1 Feb 2008
Ikeda Kazuyuki, Ihara Kenji, Yamaguchi Kenichiro, Muneuchi Jun, Ohno Takuro, Mizuno Yumi, Hara Toshiro
Abstract excerpt
Kawasaki disease (KD) is an acute febrile disorder characterized by systemic vasculitis primarily occurring in coronary arteries. Matrix metalloproteinases (MMPs) have been considered to play pathophysiologic roles in the development of coronary artery lesions (CALs); therefore, an evaluation of the genetic contributions of the MMP genes to the development of CALs in KD patients would be beneficial for the...
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