Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role of VLA-4/VCAM-1 pathway in the establishment of CD8+ T-cell-mediated Trypanosoma cruzi-elicited meningoencephalitis.

Journal of neuroimmunology - 1 Sept 2003

Roffê Ester, Silva Andrea A, Marino Ana Paula M P, dos Santos Paula V A, Lannes-Vieira Joseli

Abstract excerpt

Central nervous system (CNS) damage can occur during Trypanosoma cruzi infection, especially in immunosuppressed patients. The enhanced susceptibility of C3H/He mice to CD8-mediated acute meningoencephalitis is associated with higher up-regulation of vascular cell adhesion molecule-1 (VCAM-1) on CNS vascular endothelia than in the less susceptible C57BL/6. Further, in vitro adhesion of activated peripheral blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Protozoan
Share to Chagas Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Immunosuppressive Agents

Share to Intercellular Adhesion Molecule-1

Share to Mice, Inbred C3H

Share to Trypanosoma cruzi

Share to Vascular Cell Adhesion Molecule-1

Source

Identifiers

PMID: 14512161
DOI: 10.1016/s0165-5728(03)00254-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role of VLA-4/VCAM-1 pathway in the establishment of CD8+ T-cell-mediated Trypanosoma cruzi-elicited meningoencephalitis.PMID 14512161Read ↗

From Invasion to Systemic Dysfunction: Pathophysiology of <em>Trypanosoma brucei</em> in Veterinary MedicineSemantic proximity Read ↗

Characteristics and critical function of CD8+ T cells in the Toxoplasma-infected brain.Semantic proximity Read ↗

Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse.Semantic proximity Read ↗

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral MalariaSemantic proximity Read ↗

Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.Semantic proximity Read ↗

<i>Trypanosoma brucei brucei</i> crosses the blood–brain barrier while tight junction proteins are preserved in a rat chronic disease modelSemantic proximity Read ↗

Vimentin contributes to the comorbidities of Cryptococcus neoformans and HIV-1 gp120Semantic proximity Read ↗

Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.Semantic proximity Read ↗

A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.Semantic proximity Read ↗

CCR5 Plays a Critical Role in the Development of Myocarditis and Host Protection in Mice Infected withTrypanosoma cruziSemantic proximity Read ↗

Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cellsSemantic proximity Read ↗

Activation of small ruminant aortic endothelial cells after in vitro infection by caprine arthritis encephalitis virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.