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[Hereditary medullary thyroid carcinoma--genotype-phenotype characterization].

Deutsche medizinische Wochenschrift (1946) - 26 Sept 2003

Frank-Raue K, Heimbach C, Rondot S, Usadel K-H, Meng W, Varma C, Fuchs-Hammoser R, Höppner W, Schulze E, Raue F

Abstract excerpt

BACKGROUND AND OBJECTIVE: Hereditary medullary thyroid carcinoma (MTC) is caused by germline mutations of the RET proto-oncogene. A genotype - phenotype correlation has been established, showing clustering of mutations in exons 10 and 11 in classical MEN 2 A syndrome, in exon 16 codon 918 in MEN 2 B syndrome and in exons 13-15 in familial MTC. A line of evidence suggested that the development and the...

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Identifiers

PMID: 14508694
DOI: 10.1055/s-2003-42555

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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