Parkinson's syndrome associated with neurofibrillary degeneration and tau pathologic findings.

Abstract excerpt

Several distinct clinical syndromes presenting with parkinsonism have been associated with subcortical neurofibrillary degeneration and the abnormal accumulation of hyperphosphorylated tau protein in the brain. Mutations of tau have been linked with a small number of autosomal dominantly inherited families who present with frontolimbic cognitive deficits, behavioural disorders, and Parkinson's syndrome. Some of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brain
• Share to Diagnosis, Differential
• Share to Mutation