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Article

One-eyed pinhead regulates cell motility independent of Squint/Cyclops signaling.

Developmental biology - 15 Sept 2003

Warga Rachel M, Kane Donald A

Abstract excerpt

In vertebrates, EGF-CFC factors are essential for Nodal signaling. Here, we show that the zygotic function of one-eyed pinhead, the zebrafish EGF-CFC factor, is necessary for cell movement throughout the blastoderm of the early embryo. During the blastula and gastrula stages, mutant cells are more cohesive and migrate slower than wild-type cells. Chimeric analysis reveals that these early motility defects are...

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Source

Identifiers

PMID: 14499649
DOI: 10.1016/s0012-1606(03)00328-2

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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