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Article

Variation in the matrix metalloproteinase-1 gene and risk of coronary heart disease.

European heart journal - 1 Sept 2003

Ye Shu, Gale Catharine R, Martyn Christopher N

Abstract excerpt

AIMS: Matrix metalloproteinase-1 (MMP-1), a proteolytic enzyme able to degrade types I and III collagens, is present in atherosclerotic lesions but absent from the normal blood vessel wall. The recent observation that, in a transgenic mouse model, MMP-1 gene expression slows the development and progression of atherosclerotic plaques suggests that it may play a role in human atherogenesis. We investigated whether...

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Source

Identifiers

PMID: 14499230
DOI: 10.1016/s0195-668x(03)00385-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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