Article

Metreleptin as A Rescue Therapy in A Patient With A Novel Mutation for Familial Partial Lipodystrophy Type 3, Originally Presenting as Type 1 Diabetes.

2021-01-28

Abstract excerpt

<h4>Background: </h4> Familial partial lipodystrophy type 3 (FPLD3) is a very rare autosomal dominant genetic disorder which is caused by mutations in the peroxisome proliferator activated receptor gamma ( PPARG ) gene. It is characterized by a partial loss of adipose tissue leading to subnormal leptin secretion and metabolic complications. Metreleptin, a synthetic analogue of human leptin, is an effective treatme...

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Literature Corpus work: 8c2b868f-5936-5cb1-908f-f5bdefd2dd7b
DOI: 10.21203/rs.3.rs-154503/v1

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