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Analysis of Circulating Tumor DNA.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Mithraprabhu Sridurga, Spencer Andrew

Abstract excerpt

Circulating tumor DNA (ctDNA) analysis is currently gaining momentum as an innovative methodology for characterizing the tumor genome and monitoring therapeutic efficacy in the multifocal, genetically and spatially heterogeneous plasma cell malignancy, multiple myeloma (MM). Circulating cell-free DNA (cfDNA), which consists of a combination of DNA derived from both tumor and normal cells, is present in...

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PMID: 29797256
DOI: 10.1007/978-1-4939-7865-6_9

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