The molecular basis for reactivity of anti-Cw1 and anti-Cw3 alloantisera with HLA-B46 haplotypes.

doi:10.1111/j.1399-0039.1992.tb01943.x

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Article

The molecular basis for reactivity of anti-Cw1 and anti-Cw3 alloantisera with HLA-B46 haplotypes.

Tissue antigens - 1 May 1992

Zemmour J, Gumperz J E, Hildebrand W H, Ward F E, Marsh S G, Williams R C, Parham P

Abstract excerpt

HLA haplotypes containing the HLA-B46 allele react with both anti-Cw1 and anti-Cw3 alloantisera, a pattern of reactivity defined as the Cw11 antigen and postulated to involve either a distinctive Cw11 allele or a duplicated HLA-C locus. From serological characterization of CIR cells transfected with B46 cDNA we now demonstrate that the anti-Cw3 reactivity with these haplotypes is solely due to the B46 molecule...

Topics

Alleles
Amino Acid Sequence
Antigen-Antibody Reactions
Artifacts
Base Sequence
Consensus Sequence
Cross Reactions
DNA
Epitopes
Genes, MHC Class II
HLA-C Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Isoantibodies

Models, Molecular

Molecular Sequence Data

Polymorphism, Genetic

Protein Conformation

Source

Open in PubMed

Identifiers

PMID: 1384166
DOI: 10.1111/j.1399-0039.1992.tb01943.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1384166-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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