Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paroxysmal nocturnal hemoglobinuria due to hereditary nucleotide deletion in the HRF20 (CD59) gene

1 Oct 1992

Abstract excerpt

HRF20 (CD59) is a membrane glycoprotein which protects cells from the membrane attack reaction of homologous complement. A patient who is completely deficient in HRF20 expression and is suffering from paroxysmal nocturnal hemoglobinuria (PNH) was studied. His parents are cousins and both have decreased HRF20 expression, suggesting that the deficiency is genetic. We established a cultured cell line (NCU1) which is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Peptidase Inhibition and Analysis
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1382994
DOI: 10.1002/eji.1830221029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Paroxysmal nocturnal hemoglobinuria due to hereditary nucleotide deletion in the HRF20 (CD59) genePMID 1382994Read ↗

Inherited Complete Deficiency of 20-Kilodalton Homologous Restriction Factor (CD59) as a Cause of Paroxysmal Nocturnal HemoglobinuriaSemantic proximity Read ↗

CD59 deficiency is associated with chronic hemolysis and childhood relapsing immune-mediated polyneuropathySemantic proximity Read ↗

Production and characterization of lymphoblastoid cell lines with the paroxysmal nocturnal hemoglobinuria phenotype.Semantic proximity Read ↗

The cellular pathogenesis of paroxysmal nocturnal haemoglobinuriaSemantic proximity Read ↗

[Establishment and identification of B cell lines with PNH phenotype].Semantic proximity Read ↗

Red cells with paroxysmal nocturnal hemoglobinuria-phenotype in patients with acute leukemia.Semantic proximity Read ↗

New insights into paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Heterogeneity in the molecular pathogenesis of paroxysmal nocturnal hemoglobinuria (PNH) syndromes and expansion mechanism of a PNH clone.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.