Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of lymphocyte phenotype and T cell receptor genotype in Felty's syndrome.

The Journal of rheumatology - 1 Jul 1992

Meliconi R, Kingsley G H, Pitzalis C, Sakkas L, Panayi G S

Abstract excerpt

Natural killer (NK) cells and CD3+ large granular lymphocytes (LGL) were investigated in patients with Felty's syndrome (FS), rheumatoid arthritis (RA) and healthy controls. In most patients with FS, NK cell number and activity were decreased. CD3+ LGL were unchanged. However, in one patient a marked expansion of CD3- CD16+ CD56+ (NK) cells was seen and in a second, an expansion of CD3+ LGL. In FS there was also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antigens, CD
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Genotype

Share to HLA-DR Antigens

Share to Killer Cells, Natural

Share to Lymphocytes

Source

Identifiers

PMID: 1380988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Analysis of lymphocyte phenotype and T cell receptor genotype in Felty's syndrome.PMID 1380988Read ↗

Phenotypic and genotypic analysis of mononuclear cells from patients with Felty's syndrome.Semantic proximity Read ↗

Hematologic and cytofluorographic analysis of patients with Felty's syndrome. A hypothesis that a discrete event leads to large granular lymphocyte expansions in this condition.Semantic proximity Read ↗

Prevalence of STAT3 mutations in patients with rheumatoid arthritis-associated T-cell large granular lymphocytic leukaemia and Felty syndrome.Semantic proximity Read ↗

Immunogenetic similarities between patients with Felty's syndrome and those with clonal expansions of large granular lymphocytes in rheumatoid arthritis.Semantic proximity Read ↗

Major histocompatility complex haplotypic associations in Felty's syndrome and large granular lymphocyte syndrome are secondary to allelic association with HLA-DRB1 *0401.Semantic proximity Read ↗

Abnormalities in the T and NK lymphocyte phenotype in patients with Nijmegen breakage syndromeSemantic proximity Read ↗

Persistent clonal expansions of CD3+TCR gamma delta+ and CD3+TCR alpha beta+CD4-CD8- lymphocytes associated with neutropenia.Semantic proximity Read ↗

Molecular analysis of T cell receptor and CD3 genes in CD3- large granular lymphocytes (LGLs): evidence for the existence of CD3- LGLs committed to the T cell lineage.Semantic proximity Read ↗

Studies of a C2 DNA polymorphism in RA, Felty's and normal subjects.Semantic proximity Read ↗

A Fas promoter polymorphism at position -670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.