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Article

Persistent clonal expansions of CD3+TCR gamma delta+ and CD3+TCR alpha beta+CD4-CD8- lymphocytes associated with neutropenia.

Leukemia & lymphoma - 1 Aug 1994

Scott C S, Richards S J, Sivakumaran M, Steed A J, Norfolk D R, Milligan D W, Short M

Abstract excerpt

This communication reports the clinical and cellular features of five elderly female patients with persistent moderate to severe neutropenia and concomitant relative expansions of CD3+TCR gamma delta+ (n = 4) or CD3+TCR alpha beta+CD4-CD8- (n = 1) lymphocyte populations. In clinical terms, severe neutropenia was the main contributing factor to patient symptoms although two additionally had long-standing histories...

Topics

Aged
Antigens, CD
Base Sequence
CD3 Complex
CD4 Antigens
CD8 Antigens
Female
Genotype
Humans
Immunophenotyping
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neutropenia

Receptors, Antigen, T-Cell, alpha-beta

Receptors, Antigen, T-Cell, gamma-delta

T-Lymphocyte Subsets

Source

Identifiers

PMID: 7812202
DOI: 10.3109/10428199409049700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7812202-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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