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Article

The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila.

Cell - 21 Aug 1992

Jongens T A, Hay B, Jan L Y, Jan Y N

Abstract excerpt

The first cell fate specification process in the Drosophila embryo, formation of the germline precursors, requires posteriorly localized germ plasm. We have cloned a gene, germ cell-less (gcl), required for germline formation. Posterior localization of the gcl messenger RNA (mRNA) requires the function of those genes essential for the localization of both nanos RNA, which specifies the abdomen, and the germ cell...

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PMID: 1380406
DOI: 10.1016/0092-8674(92)90427-e

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The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila.PMID 1380406Read ↗

germ cell-less is required only during the establishment of the germ cell lineage of Drosophila and has activities which are dependent and independent of its localization to the nuclear envelope.Semantic proximity Read ↗

The Role of Nanos in Germ Granules—Putative Posttranscriptional Regulation Hubs in Germ Cell Specification and Development Across SpeciesSemantic proximity Read ↗

Genetics of nanos localization in Drosophila.Semantic proximity Read ↗

spoonbill, a new Drosophila female-sterile mutation, interferes with chromosome organization and dorsal-ventral patterning of the egg.Semantic proximity Read ↗

Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.Semantic proximity Read ↗

Specification of the germ lineSemantic proximity Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

Maintaining sufficient nanos is a critical function for polar granule component in the specification of primordial germ cells.Semantic proximity Read ↗

Somatic gene repression ensures physical segregation of germline and soma in <i>Drosophila</i> embryosSemantic proximity Read ↗

Conserved role of nanos proteins in germ cell development.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo.Semantic proximity Read ↗

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