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Article

Regulatory mutants and transcriptional control of the Serratia marcescens extracellular nuclease gene.

Molecular microbiology - 1 Mar 1992

Chen Y C, Shipley G L, Ball T K, Benedik M J

Abstract excerpt

The extracellular nuclease of Serratia marcescens is regulated in a complex fashion. Unlike most catabolic enzymes, it appears not to be substrate regulated. However we have shown it to be regulated by an SOS-like system in S. marcescens. Additionally nuclease expression is regulated in a growth-phase-dependent manner. In this work we demonstrate that growth-phase-dependent regulation is at the transcriptional...

Topics

Amino Acid Sequence
Base Sequence
Cell Cycle
Chromosome Mapping
DNA, Bacterial
Endodeoxyribonucleases
Endonucleases
Endoribonucleases
Gene Expression Regulation, Bacterial
Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Promoter Regions, Genetic

RNA, Bacterial

Regulatory Sequences, Nucleic Acid

SOS Response, Genetics

Serratia marcescens

Transcription, Genetic

Source

Identifiers

PMID: 1372678
DOI: 10.1111/j.1365-2958.1992.tb01512.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1372678-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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