Article
Chromosome 14 in B10.A(18R) mice is recombinant and includes Tcra-Va alleles.
Immunogenetics - 1 Jan 1992
Nakajima P B, Di Vincenzo J P, Jameson S C, Gascoigne N R
Abstract excerpt
Analysis of mouse Tcr genes has previously defined at least five different Tcra-V haplotypes among inbred strains of mice. For mice of the Tcra-Vb haplotype, including C57BL/10 (B10), T-cell expression of the Tcra-V11 gene subfamily can be detected with a monoclonal antibody, 1.F2. In the course of further characterizing the specificity of 1.F2, we found that it fails to recognize Tcra-V11-expressing T-cell...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Epitopes
- Haplotypes
- Mice
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell, alpha-beta
