Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression.

doi:10.1128/JVI.66.1.95-105.1992

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Article

Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression.

Journal of virology - 1 Jan 1992

Colberg-Poley A M, Santomenna L D, Harlow P P, Benfield P A, Tenney D J

Abstract excerpt

We have established the ability of the human cytomegalovirus (HCMV) UL36-38 and US3 immediate-early (IE) gene products to alter gene expression in human cells by using transient transfection assays. The cellular heat shock protein 70 (hsp70) promoter was transactivated following cotransfection with the HCMV IE regions in nonpermissive HeLa cells by UL36-38, US3, or IE1 and in permissive human diploid fibroblasts...

Topics

Amino Acid Sequence
Base Sequence
Cells, Cultured
Cytomegalovirus
DNA, Viral
Gene Expression Regulation, Viral
HeLa Cells
Heat-Shock Proteins
Humans
Immediate-Early Proteins
Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Promoter Regions, Genetic

RNA

Sequence Alignment

Trans-Activators

Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 1370097
DOI: 10.1128/JVI.66.1.95-105.1992
PMCID: PMC238264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1370097-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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