Article
Measuring and increasing protein stability.
Trends in biotechnology - 1 Apr 1990
Pace C N
Abstract excerpt
Recently, it has become possible to construct proteins to order and this has promoted interest in learning how to increase their stability. This article describes recent developments in the methods used to measure the conformational stability of globular proteins, and discusses the approaches being used to increase their stability.
Topics
- Globulins
- Mutation
- Protein Conformation
- Protein Denaturation
- Protein Engineering
- Ribonuclease T1
- Thermodynamics