Article
Phylogenetic analysis of the cadherin superfamily.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Nov 1992
Pouliot Y
Abstract excerpt
Cadherins are a multigene family of proteins which mediate homophilic calcium-dependent cell adhesion and are thought to play an important role in morphogenesis by mediating specific intercellular adhesion. Different lines of experimental evidence have recently indicated that the site responsible for mediating adhesive interactions is localized to the first extracellular domain of cadherin. Based upon an analysis...
Topics
- Amino Acid Sequence
- Animal Population Groups
- Animals
- Cadherins
- Cell Adhesion
- Humans
- Molecular Sequence Data
- Morphogenesis
- Multigene Family
- Mutation
- Phylogeny
- Protein Structure, Tertiary
