Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex.

Proceedings of the National Academy of Sciences of the United States of America - 7 Aug 2012

Nichols Scott Anthony, Roberts Brock William, Richter Daniel Joseph, Fairclough Stephen Robert, King Nicole

Abstract excerpt

The evolution of cadherins, which are essential for metazoan multicellularity and restricted to metazoans and their closest relatives, has special relevance for understanding metazoan origins. To reconstruct the ancestry and evolution of cadherin gene families, we analyzed the genomes of the choanoflagellate Salpingoeca rosetta, the unicellular outgroup of choanoflagellates and metazoans Capsaspora owczarzaki,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Cadherins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Computational Biology

Share to DNA Primers

Share to Evolution, Molecular

Share to Genome

Share to Genomic Library

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 22837400
DOI: 10.1073/pnas.1120685109
PMCID: PMC3420208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex.PMID 22837400Read ↗

Gene family innovation, conservation and loss on the animal stem lineage.Semantic proximity Read ↗

Phylogenetic analysis of the cadherin superfamily.Semantic proximity Read ↗

The evolutionary history of the catenin gene family during metazoan evolutionSemantic proximity Read ↗

The Rosetteless gene controls development in the choanoflagellate S. rosetta.Semantic proximity Read ↗

Orthologs at the Base of the Olfactores CladeSemantic proximity Read ↗

Multigene phylogeny of choanozoa and the origin of animals.Semantic proximity Read ↗

Protein evolution: structure-function relationships of the oncogene beta-catenin in the evolution of multicellular animals.Semantic proximity Read ↗

Nonchordate classic cadherins have a structurally and functionally unique domain that is absent from chordate classic cadherins.Semantic proximity Read ↗

T-cadherin structures reveal a novel adhesive binding mechanism.Semantic proximity Read ↗

The CKK Domain (DUF1781) Binds Microtubules and Defines the CAMSAP/ssp4 Family of Animal ProteinsSemantic proximity Read ↗

Co-Option and De Novo Gene Evolution Underlie Molluscan Shell Diversity.Semantic proximity Read ↗

An organismal perspective on C. intestinalis development, origins and diversification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.